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doi: 10.1007/978-1-4419-8216-2_7 498 ManianFA

Severe or continuing vomiting or diarrhea can lead to dehydration, which may harm the kidneys

Unlike classical inflammation (characterized by heat, redness, and pain), neuroinflammation primarily involves the release of pro-inflammatory mediators (e.g., cytokines, chemokines, and ROS) by resident immune cells, particularly microglia, the CNSs innate immune effectors [110, 111]

While results may develop more gradually than with some aggressive treatments, the improvements tend to be more sustainable and come without the risk of long-term damage or irritation that can accompany harsher approaches

These studies of isolated compounds from M